Vol 10, No 8 (April 29, 2022): Annals of Translational Medicine

Original Article

Prognostic role of immune microenvironment in pleural metastases from breast and lung adenocarcinomas
Georgia Karpathiou, Jonas Benli, Anne Laure Désage, Mathilde Jacob, Olivier Tiffet, Michel Peoc’h, Marios E. Froudarakis
Annals of Translational Medicine
 2022;
10
(8)
:430
cGAS/STING signaling in the regulation of rheumatoid synovial aggression
Ruiru Li, Wei Lin, Yu Kuang, Jingnan Wang, Siqi Xu, Chuyu Shen, Qian Qiu, Maohua Shi, Youjun Xiao, Liuqin Liang, Hanshi Xu
Annals of Translational Medicine
 2022;
10
(8)
:431
Melatonin exerts anti-angiogenic and anti-inflammatory effects in alkali-burned corneas
Jie Meng, Bingying Lin, Siyu Huang, Yangyang Li, Pengsen Wu, Fan Zhang, Yu Ke, Xiangqing Hei, Danping Huang
Annals of Translational Medicine
 2022;
10
(8)
:432
Nonsustained atrial tachycardia in 24-hour Holter monitoring: a potential cardiac source of embolism in acute ischemic stroke
Taedong Ok, Seung Ha Lee, Jong-Youn Kim, Kyung-Yul Lee, Yo Han Jung
Annals of Translational Medicine
 2022;
10
(8)
:433
Promising role of liver transplantation in patients with combined hepatocellular-cholangiocarcinoma: a propensity score matching analysis
Xiaoyuan Chen, Shiquan Sun, Yiwei Lu, Xiaoli Shi, Ziyi Wang, Xuejiao Chen, Guoyong Han, Jie Zhao, Yun Gao, Xuehao Wang
Annals of Translational Medicine
 2022;
10
(8)
:434
Does fructose have a protective role on migraine?—experimental evidence in a rat model of metabolic syndrome under omega-3 supplementation
Isadora R. Barbosa, Gabriela da Cunha, Rodrigo B. M. Silva, Raquel D. S. Freitas, Ana P. A. Dagnino, Maria M. Campos
Annals of Translational Medicine
 2022;
10
(8)
:435
A modified impactor for establishing a graded contusion spinal cord injury model in rats
Rongbao Yan, Erliang Li, Kang Yan, Qian Zhang, Yanhua Wen, Rui Zhang, Yonghong Wu, Jin Sun, Xin Dong, Qiong Ma, Bo Liao
Annals of Translational Medicine
 2022;
10
(8)
:436
Effects of the posterior cruciate ligament and tibia insert thickness on tibiofemoral joint pressure in total knee arthroplasty: a cadaveric study
Xing Xin, Hong Cai, Zhongqiang Chen
Annals of Translational Medicine
 2022;
10
(8)
:437
Relationship between postoperative complications of esophageal cancer surgery and season: a retrospective study
Xianben Liu, Kun Gao, Wenqun Xing, Zongfei Wang, Haibo Sun, Yan Zheng
Annals of Translational Medicine
 2022;
10
(8)
:438
Fraxetin alleviates microglia-mediated neuroinflammation after ischemic stroke
Shi-Ji Deng, Jian-Wei Ge, Sheng-Nan Xia, Xin-Xin Zou, Xin-Yu Bao, Yue Gu, Yun Xu, Hai-Lan Meng
Annals of Translational Medicine
 2022;
10
(8)
:439
Effect of treatment modality on the long-term survival of patients with early glottic squamous cancer: a retrospective cohort study based on the SEER database
Wen-Lun Wang, Hong-Wei Zheng, Li-Hong Zhang, Li-Sheng Yu
Annals of Translational Medicine
 2022;
10
(8)
:440
Efficacy and safety of camrelizumab plus apatinib as second-line treatment for advanced squamous non-small cell lung cancer
Guanghui Gao, Jun Zhao, Shengxiang Ren, Yina Wang, Gongyan Chen, Jianhua Chen, Kangsheng Gu, Renhua Guo, Yueyin Pan, Quanren Wang, Weixia Li, Xinfeng Yang, Caicun Zhou
Annals of Translational Medicine
 2022;
10
(8)
:441
Molecular characterization of vascular intestinal obstruction using whole-exome sequencing
Zhong Ji, Zhaohui Du, Chuanming Zheng, Hehe Dou, Hai Jiang, Xing Wang, Zhenjie Wang
Annals of Translational Medicine
 2022;
10
(8)
:442
Diagnostic yield of virtual bronchoscope navigation combined with radial endobronchial ultrasound guided transbronchial cryo-biopsy for peripheral pulmonary nodules: a prospective, randomized, controlled trial
Yong Liu, Feng Wang, Quncheng Zhang, Zhaohui Tong
Annals of Translational Medicine
 2022;
10
(8)
:443
Screening and identification of osteoarthritis related differential genes and construction of a risk prognosis model based on bioinformatics analysis
Ran You, Siyi Liu, Jinhai Tan
Annals of Translational Medicine
 2022;
10
(8)
:444
Efficacy and safety of drug-coated balloons in the treatment of de novo coronary lesions in very small vessels: a prospective, multicenter, single-arm trial
Mingduo Zhang, Jingwen Yong, Yuan Zhou, Min Zhang, Xiantao Song, Shubin Qiao, Lefeng Wang, Qian Tong, Li Zhang, Bei Shi
Annals of Translational Medicine
 2022;
10
(8)
:445
Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway
Huilin Peng, Ming Wei, Lianjing Huang, Yaqin Yan, Qing Li, Sujuan Li, Yichi Wu, Yuan Gao, Ying Xing, Xiaoping Luo
Annals of Translational Medicine
 2022;
10
(8)
:446
The feasibility of uterine-vaginal axis MRI-based as evaluation of surgical efficacy in women with pelvic organ prolapse
Haifeng Wang, Jihong Shen, Song Li, Zhenhua Gao, Kunbin Ke, Peng Gu
Annals of Translational Medicine
 2022;
10
(8)
:447
Identification of significant genes with a poor prognosis in skin cutaneous malignant melanoma based on a bioinformatics analysis
Jin Wang, Jilong Yang
Annals of Translational Medicine
 2022;
10
(8)
:448
Metabonomic analysis of cerebrospinal fluid in epilepsy
Di Niu, Pin Sun, Fenghua Zhang, Fan Song
Annals of Translational Medicine
 2022;
10
(8)
:449
Adipose-derived mesenchymal stem cells combined with platinum nanoparticles accelerate fracture healing in a rat tibial fracture model
Chuan-Jie Chen, Yuan Feng, Lin Jin, Xin Wang, Li-xiao-zi Xu, Jia-Mei Lin, Li-Wen Feng, Li-Na Liu, Zhiyong Hou
Annals of Translational Medicine
 2022;
10
(8)
:450
Intraoperative salvaging of failure to harvest the bi-paddle anterolateral thigh flap: a case series
Xi Yang, Wenqian Mo, Yongqing Xu, Wuhua Liu, Yan Shi, Xiang Fang, Yujian Xu, Xiaoqing He
Annals of Translational Medicine
 2022;
10
(8)
:451
Neoadjuvant radiotherapy for soft tissue sarcoma in China: a preliminary result
Zhen Huang, Ning Li, Yuan Tang, Jing Jin, Weifeng Liu, Hairong Xu, Feng Yu, Lin Hao, Qing Zhang, Yi Ding, Xiaohui Niu
Annals of Translational Medicine
 2022;
10
(8)
:452
Potential mechanisms of Qili Qiangxin capsule to prevent pulmonary arterial hypertension based on network pharmacology analysis in a rat model
Xiao Han, Chao Li, Ping Yang, Tingbo Jiang
Annals of Translational Medicine
 2022;
10
(8)
:453
Long non-coding RNA MEG3 regulates the progress of osteoarthritis by regulating the miR-34a/Klotho axis
Gaoxin Xiong, Shuangli Wang, Zhengjun Pan, Ning Liu, Donglei Zhao, Zhengang Zha, Rende Ning
Annals of Translational Medicine
 2022;
10
(8)
:454
Tonifying-Qi-and-Detoxification Decoction attenuated injuries of colon and lung tissues in ulcerative colitis rat model via regulating NF-κB and p38MAPK pathway
Xin Yan, Xue Yu, Chunhua Jiang, Ying Cao, Liang Zhu, Chenguang Du, Yongsen Jia
Annals of Translational Medicine
 2022;
10
(8)
:455
Oncostatin M promotes the ox-LDL-induced activation of NLRP3 inflammasomes via the NF-κB pathway in THP-1 macrophages and promotes the progression of atherosclerosis
Cheng Liu, Jiang Wu, Haiyun Jia, Caixia Lu, Junjun Liu, Yongxin Li, Mingjin Guo
Annals of Translational Medicine
 2022;
10
(8)
:456
The preoperative hemoglobin, albumin, lymphocyte, and platelet score is a prognostic factor for non-small cell lung cancer patients undergoing adjuvant chemotherapy: a retrospective study
Sheng Wei, Jingjing Shao, Jinming Wang, Gaoren Wang
Annals of Translational Medicine
 2022;
10
(8)
:457
A comparative study of changes in audiological characteristics when using endoscopic and microscopic stapes surgery in patients with otosclerosis
Yiyang Tang, Minqian Gao, Tao Zhang, Haidi Yang
Annals of Translational Medicine
 2022;
10
(8)
:458
Apatinib enhances the antitumor effects of radiation in HeLa cell line mouse model of invasive cervical cancer
Yun Wang, Li Zhang, Wei Liu, Jing-Pin Yang, Hong-Ju Peng, Jian-Wen Zhang
Annals of Translational Medicine
 2022;
10
(8)
:459
Association between chronic illness resources and health behaviors in hypertensive stroke patients at 6 months after discharge: a cross-sectional study
Ke Wen, Meng-Jie Shen, Cheng-Song Deng, Yue-Feng Li, Ya-Nan Kang, Li-Hong Wan
Annals of Translational Medicine
 2022;
10
(8)
:460
Analysis of influencing factors on the plasma concentration of first-line anti-tuberculosis drugs-a single-center retrospective cohort study
Guanren Zhao, Ming Chen, Lijun Sun, Na Xi
Annals of Translational Medicine
 2022;
10
(8)
:461
The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based somatic variation profiling
Ling Qin, Ting Guo, Huaping Yang, Pengbo Deng, Qihua Gu, Chi Liu, Mengping Wu, Analyn Lizaso, Bing Li, Sa Zhang, Zhiqiu Chen, Chengping Hu
Annals of Translational Medicine
 2022;
10
(8)
:462
Hyperthermia enhances the efficacy of chemotherapeutic drugs in heat-sensitive cells through interfering with DNA damage repair
Li-Ping Ni, Hua-Ting Sun, Ping Wang, Juan Wang, Jin-Hua Zhou, Ruo-Qi Cao, Ling Yue, You-Guo Chen, Fang-Rong Shen
Annals of Translational Medicine
 2022;
10
(8)
:463
An N6-methyladenosine-associated lncRNA signature for predicting clinical outcome and therapeutic responses in hepatocellular carcinoma
Danjun Song, Yingming Tian, Jun Luo, Guoliang Shao, Jiaping Zheng
Annals of Translational Medicine
 2022;
10
(8)
:464
The effect of TLR-4 on the proliferation and differentiation of bone mesenchymal stem cells and its relationship with the Wnt signal transduction pathway during bone nonunion
Gang Mei, Yan Zhao, Zhenlv Zou, Yongming Liu, Xin Jiang, Yafei Xu, Wende Xiao
Annals of Translational Medicine
 2022;
10
(8)
:465
The value of WNT5A as prognostic and immunological biomarker in pan-cancer
Yingtong Feng, Yuanyong Wang, Kai Guo, Junjun Feng, Changjian Shao, Minghong Pan, Peng Ding, Honggang Liu, Hongtao Duan, Di Lu, Zhaoyang Wang, Yimeng Zhang, Yujing Zhang, Jing Han, Xiaofei Li, Xiaolong Yan
Annals of Translational Medicine
 2022;
10
(8)
:466
Feasibility of lattice radiotherapy using proton and carbon-ion pencil beam for sinonasal malignancy
Dong Yang, Weiwei Wang, Jiyi Hu, Weixu Hu, Xiyu Zhang, Xiaodong Wu, Jiade J. Lu, Lin Kong
Annals of Translational Medicine
 2022;
10
(8)
:467
MMP2/9 downregulation is responsible for hepatic function recovery in cirrhotic rats following associating liver partition and portal vein ligation for staged hepatectomy
Yugang Qin, Chonghui Li, Xinlan Ge, Qiang Zhang, Xiaojun Wei, Rong Liu
Annals of Translational Medicine
 2022;
10
(8)
:468
Changes in inpatient admissions before and during COVID-19 outbreak in a large tertiary hospital in Shanghai
Ya Yang, Ke-Jia Le, Chen Liang, Tao Zheng, Zhi-Chun Gu, Hou-Wen Lin, Ji-Dong Zhang, Hua-Jie Luo
Annals of Translational Medicine
 2022;
10
(8)
:469
The diagnostic value of endoplasmic reticulum stress-related specific proteins GRP78 and CHOP in patients with sepsis: a diagnostic cohort study
Fangfang Li, Qionghua Lin, Lihua Shen, Zhongwei Zhang, Pengmei Wang, Shan Zhang, Qian Xing, Zhili Xia, Zhiyong Zhao, Yunhe Zhang, Biao Zhu
Annals of Translational Medicine
 2022;
10
(8)
:470
Diagnostic test of bioimpedance-based neural network algorithm in early cervical cancer
Ling Mei, Jian Meng, Dongmei Wei, Qian Hu, Yueyue Chen, Tao Cui, Yueting Zhang, Qiao Li, Xiaoli Zhang, Yuqing Liu, Qian Wang, Lisha Ding, Tao Wang, Yukuan Feng, Wei Lei, Yanhui Deng, Xiaoyun Gong, Jingchun Ling, Xiaoyu Niu
Annals of Translational Medicine
 2022;
10
(8)
:471
Abnormal neutrophil polarization in chronic obstructive pulmonary disease and how cigarette smoke extracts attract neutrophils
Fan Deng, Shaobo Zhong, Changhui Yu, Haijin Zhao, Hui Huang, Xiaojing Meng, Changqin Lin, Shaoxi Cai
Annals of Translational Medicine
 2022;
10
(8)
:472
Expression of colorectal neoplasia differentially expressed in anaplastic thyroid carcinoma and its effect on cancer cell proliferation
Lili Du, Qingsong Zhao, Jingjing Li, Mingli Wang, Hong Qiao
Annals of Translational Medicine
 2022;
10
(8)
:473
The diagnostic value of diffusion kurtosis imaging in Parkinson’s disease: a systematic review and meta-analysis
Qilin Li, Jinfeng Cao, Xinjiang Liu, Xin Luo, Ge Su, Dejian Wang, Bo Lin
Annals of Translational Medicine
 2022;
10
(8)
:474
Bromodomain-containing protein 4 activates cardiotrophin-like cytokine factor 1, an unfavorable prognostic biomarker, and promotes glioblastoma in vitro
Shang-Hang Shen, Jian-Feng Guo, Ju Huang, Qian Zhang, Yi Cui
Annals of Translational Medicine
 2022;
10
(8)
:475
EB1089 promotes the expression of vitamin D receptor in the intestinal epithelial cell line HT-29 and reduces lipopolysaccharide-induced inflammatory response
Dong Lu, Minghui Yu, Lu Chen, Jianqiang Ye, Liquan Huang, Guangwei Zhu, Bin Lan
Annals of Translational Medicine
 2022;
10
(8)
:476
Operable hepatitis B virus-related hepatocellular carcinoma: gut microbiota profile of patients at different ages
Yu-Chong Peng, Jing-Xuan Xu, Chuan-Fa Zeng, Xin-Hua Zhao, Xue-Mei You, Ping-Ping Xu, Le-Qun Li, Lu-Nan Qi
Annals of Translational Medicine
 2022;
10
(8)
:477
Clostridium butyricum inhibits the progression of colorectal cancer and alleviates intestinal inflammation via the myeloid differentiation factor 88 (MyD88)-nuclear factor-kappa B (NF-κB) signaling pathway
Mingyao Zhou, Wei Yuan, Bing Yang, Wei Pei, Jie Ma, Qiang Feng
Annals of Translational Medicine
 2022;
10
(8)
:478
A comprehensive characterization of alternative splicing events related to prognosis and the tumor microenvironment in lung adenocarcinoma
Shouzheng Ma, Jun Zhu, Mengmeng Wang, Tenghui Han, Jianfei Zhu, Runmin Jiang, Tao Jiang
Annals of Translational Medicine
 2022;
10
(8)
:479
Cost-effectiveness analysis of vonoprazan versus proton pump inhibitors in the treatment of reflux esophagitis in China
Zhenhua Wang, Ruixiaotong Sun, Yanan Sheng, Shuli Qu, Lu Dong, Bin Wu
Annals of Translational Medicine
 2022;
10
(8)
:480
Sodium-glucose co-transporter 1 (SGLT1) differentially regulates gluconeogenesis and GLP-1 receptor (GLP-1R) expression in different diabetic rats: a preliminary validation of the hypothesis of “SGLT1 bridge” as an indication for “surgical diabetes”
Hengliang Zhu, Huajie Cai, Xiaokun Wang, Tao Chen, Chaohui Zhen, Zhenzhan Zhang, Xiaojiao Ruan, Guoxin Li
Annals of Translational Medicine
 2022;
10
(8)
:481
Methodological study of directed differentiation of pluripotent stem cells into corneal endothelial cells
Liexi Jia, Yumei Diao, Yifan Fang, Kunkun Yang, Liqiang Wang, Yifei Huang
Annals of Translational Medicine
 2022;
10
(8)
:482
Effect of acellular nerve scaffold containing human umbilical cord-derived mesenchymal stem cells on nerve repair and regeneration in rats with sciatic nerve defect
Chuang Qian, Zhiqiang Zhang, Rui Zhao, Dahui Wang, Hao Li
Annals of Translational Medicine
 2022;
10
(8)
:483
The relationship between anal disease and quality of life: a bibliometric study
Yanjun Liu, Luan Wang, Jieping Liu, Fei Geng, Yuan Li, Lihua Zheng
Annals of Translational Medicine
 2022;
10
(8)
:484
Berberine induces non-small cell lung cancer apoptosis via the activation of the ROS/ASK1/JNK pathway
Qianqian Chen, Yaqin Hou, Dan Li, Zhou Ding, Xiao Xu, Bingjie Hao, Qing Xia, Ming Li, Lihong Fan
Annals of Translational Medicine
 2022;
10
(8)
:485
Heterogeneous microenvironment analysis to explore the potential regulatory role of endothelial-mesenchymal transition in idiopathic pulmonary fibrosis
Yinning Xu, Xiaoping Hu, Yiwen Zhang, Zongfu Pan, Zhiyong Sun, Zhongjie Huang, Shuilian Zheng, Hansheng Pan, Xiaozhou Zou, Ping Huang
Annals of Translational Medicine
 2022;
10
(8)
:486
Identification of immune-related diagnostic markers in primary Sjögren’s syndrome based on bioinformatics analysis
Qingle Zeng, Jing Wen, Leting Zheng, Wen Zeng, Shuyuan Chen, Cheng Zhao
Annals of Translational Medicine
 2022;
10
(8)
:487
Short-term and long-term outcomes of natural orifice specimen extraction surgeries (NOSES) in rectal cancer: a comparison study of NOSES and non-NOSES
Qian Zhang, Meng Wang, Dening Ma, Weiyuan Zhang, Hongyu Wu, Yuchen Zhong, Chaojing Zheng, Haixing Ju, Guiyu Wang
Annals of Translational Medicine
 2022;
10
(8)
:488
Structured training curriculums for transanal total mesorectal excision in China: refinement is needed
Ximo Xu, Zhenghao Cai, Hong Zhang, Qing Xu, Mingyang Ren, Abe Fingerhut, Dachong Sha, Minhua Zheng, Jianwen Li, Yang Deng, Xiao Yang, Sen Zhang, Batuer Aikemu, Wei Qin, Duohuo Shu, Xinxiang Li, Jun You, Quan Wang, Bo Feng
Annals of Translational Medicine
 2022;
10
(8)
:489
Synergistic efficacy of homoharringtonine and venetoclax on acute myeloid leukemia cells and the underlying mechanisms
Fangfang Yuan, Dongbei Li, Gangping Li, Cheng Cheng, Xudong Wei
Annals of Translational Medicine
 2022;
10
(8)
:490
The prognostic and predictive value of mismatch repair status in patients with locally advanced rectal cancer following neoadjuvant therapy
Zehua Wu, Huabin Hu, Chao Wang, Jianwei Zhang, Yue Cai, Xiaoyu Xie, Yan Huang, Yanhong Deng
Annals of Translational Medicine
 2022;
10
(8)
:491
DNAJC12 activated by HNF1A enhances aerobic glycolysis and drug resistance in non-small cell lung cancer
Jin Wang, Haihua Huang, Fabing Liu
Annals of Translational Medicine
 2022;
10
(8)
:492

Case Report

Sofosbuvir and ledipasvir decreased nephrotic syndrome caused by IgA nephropathy with a membranoproliferative pattern of injury in hepatitis C virus-induced cirrhosis: a case report
Xiaohao Zhang, Jing Zhou, Canming Li, Jialing Rao, Yuanqing Li, Jun Zhang, Hui Peng
Annals of Translational Medicine
 2022;
10
(8)
:494
Surgical treatment of femoroacetabular impingement in a patient with Stickler syndrome: a case report
Yiou Wang, Yanyan Bian, Xi Chen, Wenwei Qian
Annals of Translational Medicine
 2022;
10
(8)
:495
Pralsetinib for the treatment of a RET-positive advanced non-small-cell lung cancer patient harboring both ANK-RET and CCDC6-RET fusions with coronary heart disease: a case report
Yan Meng, Lulu Li, Huan Wang, Xiaofang Chen, Yali Yue, Meiqing Wang, Lingru Meng, Bafei Li, Xiao Li
Annals of Translational Medicine
 2022;
10
(8)
:496
A case report and literature review: diagnosis and treatment of human immunodeficiency virus coinfected with visceral leishmania by metagenomic next-generation sequencing in China
Congchen Tang, Sike He, Neng Wang, Liyu Chen
Annals of Translational Medicine
 2022;
10
(8)
:497